Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 14/20 | 0.40 |
| ▸ | SCN1A | P35498 | 13/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904096 | 0.87 | NPC1 (0.40) | SCN8ASCN1AUTS2RSMN1; SMN2ALDH1A1 | |
| SCHEMBL1008624 | 0.87 | GPR119 (0.47) | SCN8ASCN1AUTS2R | |
| SCHEMBL1006626 | 0.80 | GPR119 (0.50) | SCN8ASCN1A | |
| SCHEMBL1003873 | 0.78 | SCN8A (0.44) | SCN8ASCN1A | |
| SCHEMBL904086 | 0.78 | NPC1 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1006128 | 0.77 | GPR119 (0.47) | SCN8ASCN1A | |
| SCHEMBL904081 | 0.77 | KDM4E (0.42) | UTS2RALDH1A1 | |
| SCHEMBL1005438 | 0.77 | SCN8A (0.47) | SCN8ASCN1A | |
| SCHEMBL1006057 | 0.77 | SCN1A (0.43) | SCN8ASCN1AUTS2R | |
| SCHEMBL1005839 | 0.77 | GPR119 (0.44) | SCN8ASCN1AUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |