Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244372 | 1.00 | LMNA (0.38) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1245566 | 1.00 | LMNA (0.38) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1245447 | 1.00 | LMNA (0.38) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL4266799 | 0.98 | LMNA (0.34) | LMNAOPRM1 | |
| SCHEMBL367893 | 0.96 | LMNA (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL4269231 | 0.96 | LMNA (0.33) | LMNADNM1OPRM1 | |
| Hydrochloric Acid SCHEMBL2293581 | 0.95 | LMNA (0.34) | LMNACYP2D6SPHK1GMNNPOLB | |
| Iodide SCHEMBL15008381 | 0.95 | LMNA (0.34) | LMNACYP2D6SPHK1GMNNPOLB | |
| Iodide SCHEMBL15053220 | 0.95 | LMNA (0.34) | LMNACYP2D6SPHK1GMNNPOLB | |
| Iodide SCHEMBL15008815 | 0.95 | LMNA (0.34) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262343-B1 | N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions | PUETTER MEDICE CHEM PHARM (DE) | 1996-01-03 | — | — | EP | claimed |
| EP-0516194-A2 | Pharmaceutical compositions containing cationic surfactants | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1992-12-02 | — | — | EP | claimed |
| EP-0258672-A2 | Cationic surfactants and pharmaceutical compositions containing them | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-03-09 | — | — | EP | claimed |
| EP-0516194-A2 | Pharmaceutical compositions containing cationic surfactants | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5143917-A | Cationic tensides for controlling infections | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1992-09-01 | — | — | US | disclosed |
| US-5133973-A | Quaternary Ammonium Cationic Surfactants, Antimetabolites | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1992-07-28 | — | — | US | disclosed |
| US-5057518-A | Substituted n-alkylpyrimidinium salts for absorbing hydrophobic drugs | MEDICE HEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1991-10-15 | — | — | US | disclosed |
| US-4874850-A | CATIONIC TENSIDES IN MICELLES WITH HYDROPHOBIC PEPTIDES; DRUG DELIVERY | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0260428-A2 | Cationic surfactants and pharmaceutical compositions containing them | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-03-23 | — | — | EP | disclosed |