Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211334 | 1.00 | THRB (0.43) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL39213 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL6740549 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL9294081 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL11677867 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL100286 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL39064 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL10390885 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL9604899 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL11355583 | 0.92 | THRB (0.47) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574162-A | CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| EP-0389424-B1 | 1-Hydrocarbyloxy hindered amine mercaptoacid esters, thioacetals, sulfides and disulfides | CIBA GEIGY AG (CH) | 1995-06-07 | — | — | EP | disclosed |
| EP-0389430-B1 | N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| US-5359069-A | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0389432-B1 | Hindered amine derivatives of triazine and hexahydrotriazine | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0389422-B1 | Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0389429-B1 | Azo compounds containing hindered amine moieties with low basicity | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0389434-B1 | Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0389420-B1 | Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0389423-A1 | Peroxide compounds containing hindered amine moieties with low basicity | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389429-A2 | Azo compounds containing hindered amine moieties with low basicity | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389434-A1 | Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389422-A2 | Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389427-A2 | Compounds containing both uv-absorber and 1-hydrocarbyloxy hindered amine moieties and stabilized compositions | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389431-A2 | N-Hydrocarbyloxy derivatives of hindered amine-substituted s-triazines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389430-A1 | N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0389421-A1 | Poly(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidine) light stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| US-3969306-A | POLYBUTADIENE | GENERAL ELECTRIC COMPANY (US) | 1976-07-13 | — | — | US | disclosed |