Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285852 | 0.86 | KDM4E (0.53) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL25285853 | 0.86 | KDM4E (0.53) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL9039909 | 0.82 | KDM4E (0.44) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL30987217 | 0.77 | KDM4E (0.51) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL422653 | 0.77 | GAA (0.64) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL4420346 | 0.76 | SMN1; SMN2 (0.64) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL26343321 | 0.75 | RAB9A (0.57) | KMT2ANPSR1GAALMNASMN1; SMN2 | |
| SCHEMBL11669455 | 0.74 | TP53 (0.51) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL5028361 | 0.74 | GAA (0.61) | MEN1KMT2AKDM4ENPSR1GAA | |
| SCHEMBL27924934 | 0.74 | GAA (0.56) | MEN1KMT2AKDM4ENPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741733-A1 | PHENYLIMINO-THIADIAZABICYCLOALKANE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1996-11-13 | — | — | EP | disclosed |