Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31136303 | 0.74 | CCR5 (0.48) | LMNACCR5ALDH1A1RAB9AKDM4E | |
| SCHEMBL901909 | 0.73 | MEN1 (0.41) | ADRB2ALDH1A1DPP4KDM4EHSD17B10 | |
| SCHEMBL3366165 | 0.72 | DPP4 (0.34) | DPP4ALOX15ALOX12 | |
| SCHEMBL27908180 | 0.72 | TAAR1 (0.39) | DPP4ALOX15ALOX12 | |
| SCHEMBL24187354 | 0.71 | DPP4 (0.48) | DPP4ALOX15ALOX12 | |
| SCHEMBL29523009 | 0.70 | GAA (0.33) | DPP4 | |
| SCHEMBL22787662 | 0.70 | GAA (0.33) | DPP4 | |
| SCHEMBL1002024 | 0.70 | SLC2A1 (0.38) | ADRB2CCR5ALDH1A1RAB9APARP1 | |
| SCHEMBL1003082 | 0.70 | CYP1A2 (0.41) | ADRB2CCR5ALDH1A1PARP1KDM4E | |
| SCHEMBL15091311 | 0.70 | DPP4 (0.33) | ADRB2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041435-A1 | PHENYLQUINAZOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |