Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041396 | 0.93 | CNR2 (0.44) | CNR2MAPTTNFSMN1; SMN2ALDH1A1 | |
| SCHEMBL9039339 | 0.87 | CNR2 (0.43) | CNR2MAPTTNFSMN1; SMN2ALDH1A1 | |
| SCHEMBL9037774 | 0.85 | NPSR1 (0.47) | CNR2SMN1; SMN2ALDH1A1CNR1NPC1 | |
| SCHEMBL6990088 | 0.83 | NPC1 (0.57) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL6988747 | 0.82 | CNR2 (0.55) | CNR2MAPTCNR1NPC1RAB9A | |
| SCHEMBL9039943 | 0.78 | CYP3A4 (0.40) | CNR2MAPTSMN1; SMN2ALDH1A1NAMPT | |
| SCHEMBL23852583 | 0.77 | TNF (0.54) | CNR2TNFCNR1 | |
| SCHEMBL9037906 | 0.77 | NPC1 (0.48) | CNR2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23852674 | 0.76 | TNF (0.50) | CNR2TNFALDH1A1CNR1 | |
| SCHEMBL6991219 | 0.75 | HRH4 (0.47) | CNR2SMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441349-B1 | Pyrroloazepine derivatives | SUNTORY LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |