Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985882 | 0.90 | PARP1 (0.49) | HDAC1HDAC6PARP1GFERHSD17B10 | |
| SCHEMBL9037585 | 0.89 | PARP1 (0.48) | HDAC1HDAC6PARP1MAPTKDR | |
| SCHEMBL9037045 | 0.89 | POLB (0.51) | HDAC1HDAC6PARP1MAPTKDR | |
| SCHEMBL9037485 | 0.88 | GFER (0.55) | HDAC1HDAC6PARP1AVPR1AMEN1 | |
| SCHEMBL8985854 | 0.88 | ALDH1A1 (0.49) | PARP1MEN1NPC1MAPTKMT2A | |
| SCHEMBL9038172 | 0.86 | PARP1 (0.48) | PARP1AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL9037295 | 0.84 | HDAC1 (0.49) | HDAC1HDAC6PARP1MEN1MAPT | |
| SCHEMBL9037842 | 0.83 | PARP1 (0.47) | HDAC1HDAC6PARP1AVPR1AKDR | |
| SCHEMBL9037545 | 0.82 | PARP1 (0.47) | PARP1AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL9038139 | 0.82 | ALDH1A1 (0.48) | HDAC1HDAC6PARP1MAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |