Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903906 | 0.89 | GPR119 (0.51) | GPR119PTGS2 | |
| SCHEMBL903891 | 0.84 | GPR119 (0.47) | GPR119PTGS2 | |
| SCHEMBL904082 | 0.84 | GPR119 (0.47) | GPR119PTGS2 | |
| SCHEMBL903960 | 0.84 | GPR119 (0.45) | GPR119PTGS2 | |
| SCHEMBL904208 | 0.83 | GPR119 (0.51) | GPR119PTGS2 | |
| SCHEMBL904105 | 0.82 | GPR119 (0.49) | GPR119PTGS2 | |
| SCHEMBL903953 | 0.82 | GPR119 (0.51) | GPR119PTGS2 | |
| SCHEMBL904123 | 0.80 | GPR119 (0.49) | GPR119PTGS2 | |
| SCHEMBL903967 | 0.80 | GPR119 (0.49) | GPR119PTGS2 | |
| SCHEMBL10068065 | 0.79 | GPR119 (0.47) | GPR119PTGS2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |