Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040269 | 1.00 | TDP1 (0.58) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9487912 | 0.94 | TDP1 (0.65) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL10517647 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL10517652 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL10517640 | 0.92 | TDP1 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9643568 | 0.91 | TDP1 (0.49) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9643587 | 0.91 | TDP1 (0.49) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9487093 | 0.90 | MAPK8 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9487096 | 0.90 | MAPK8 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT | |
| SCHEMBL9487088 | 0.90 | MAPK8 (0.50) | TDP1ALDH1A1MAPK8GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1146867-A | — | — | None | — | — | JP | disclosed |
| EP-0312243-B1 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LTD (GB) | 1996-08-07 | — | — | EP | disclosed |
| US-5198444-A | Methyl α-(2-substituted)pyrid-3-yl-β-methoxyacrylates, compositions containing them and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5158954-A | For agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-27 | — | — | US | disclosed |
| US-5008276-A | Plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |
| JP-H01146867-A | FUNGICIDAL COMPOUND, ITS PRODUCTION AND FUNGICIDAL COMPOSITION USING THE SAME | IMPERIAL CHEM IND PLC <ICI> | 1989-06-08 | — | — | JP | disclosed |
| EP-0312243-A2 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |