Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517640 | 1.00 | TDP1 (0.50) | TDP1MAPK8KMT2AHPGDMEN1 | |
| SCHEMBL10517647 | 1.00 | TDP1 (0.50) | TDP1MAPK8KMT2AHPGDMEN1 | |
| SCHEMBL9643587 | 0.94 | TDP1 (0.49) | TDP1MAPK8KMT2AHPGDMEN1 | |
| SCHEMBL9643568 | 0.94 | TDP1 (0.49) | TDP1MAPK8KMT2AHPGDMEN1 | |
| SCHEMBL9040269 | 0.92 | TDP1 (0.58) | TDP1MAPK8KMT2AALDH1A1MAPT | |
| SCHEMBL9040273 | 0.92 | TDP1 (0.58) | TDP1MAPK8KMT2AALDH1A1MAPT | |
| SCHEMBL9487135 | 0.90 | ALDH1A1 (0.49) | TDP1MAPK8KMT2AHTTALDH1A1 | |
| SCHEMBL9487122 | 0.90 | ALDH1A1 (0.49) | TDP1MAPK8KMT2AHTTALDH1A1 | |
| SCHEMBL9487132 | 0.90 | ALDH1A1 (0.49) | TDP1MAPK8KMT2AHTTALDH1A1 | |
| SCHEMBL9486942 | 0.90 | TDP1 (0.49) | TDP1MAPK8KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312243-A2 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |