Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044125 | 0.93 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL9041556 | 0.93 | AGTR1 (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042283 | 0.90 | AGTR1 (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL9041791 | 0.90 | PPARG (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL9043113 | 0.90 | AGTR1 (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL8788433 | 0.90 | AGTR1 (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL9041377 | 0.89 | AGTR1 (0.74) | PPARGAGTR1AGTR2 | |
| SCHEMBL9700114 | 0.89 | AGTR1 (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042978 | 0.89 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042244 | 0.89 | PPARG (0.60) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |