Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040584 | 1.00 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL9040242 | 0.78 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL9040236 | 0.78 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL22260289 | 0.77 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL25968608 | 0.77 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL28791101 | 0.76 | KHK (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6002481 | 0.72 | POLB (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL23064603 | 0.70 | KHK (0.48) | — | |
| SCHEMBL5530870 | 0.70 | KHK (0.48) | — | |
| SCHEMBL23064604 | 0.70 | KHK (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734379-A1 | NOVEL 2-ARYLALKENYL-AZACYCLOALKANE DERIVATIVES AS SIGMA RECEPTOR LIGANDS, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1996-10-02 | — | — | EP | disclosed |