Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 9/20 | 0.39 |
| ▸ | ESR1 | P03372 | 9/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038778 | 0.92 | TOP1 (0.35) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL7838037 | 0.91 | MALT1 (0.32) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL7839314 | 0.86 | MAPT (0.37) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL9065893 | 0.83 | HRAS (0.39) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL7759399 | 0.83 | KDM4E (0.49) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL9038223 | 0.82 | HRAS (0.49) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL7762983 | 0.80 | KDM4E (0.35) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL8692462 | 0.79 | HRAS (0.48) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL6613308 | 0.78 | KDM4E (0.49) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL9039315 | 0.78 | HRAS (0.42) | HRASESR1ESR2TOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722446-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996005196-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA S.P.A. (IT) | 1996-02-22 | — | — | WO | disclosed |