⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843370 | 0.89 | ALDH1A1 (0.53) | — | |
| SCHEMBL919246 | 0.77 | — | — | |
| SCHEMBL3626599 | 0.77 | MAPT (0.49) | — | |
| SCHEMBL11441748 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL15279098 | 0.73 | — | — | |
| SCHEMBL13660532 | 0.73 | — | — | |
| SCHEMBL835383 | 0.72 | — | — | |
| 2-Ethylfuran SCHEMBL29159372 | 0.72 | — | — | |
| SCHEMBL28413600 | 0.71 | — | — | |
| SCHEMBL414949 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5141930-A | Antianxietic drug, antipsychotics and cardiotonic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |