Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040757 | 0.81 | HPGD (0.37) | HPGDKDM4EUSP2CYP4F2CYP4A11 | |
| SCHEMBL25286184 | 0.78 | CYP4F2 (0.43) | HPGDUSP2TSHRTDP1CYP4F2 | |
| SCHEMBL25242327 | 0.78 | CYP4F2 (0.43) | HPGDUSP2TSHRTDP1CYP4F2 | |
| SCHEMBL10917876 | 0.78 | ALDH1A1 (0.45) | HPGDKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL9118279 | 0.78 | KDM4E (0.33) | HPGDKDM4ETSHRCYP4F2CYP4A11 | |
| SCHEMBL10915365 | 0.71 | MEN1 (0.46) | HPGDKDM4ETSHRTDP1L3MBTL1 | |
| SCHEMBL10917035 | 0.71 | ALDH1A1 (0.47) | HPGDKDM4ETSHRTDP1L3MBTL1 | |
| SCHEMBL9118826 | 0.69 | NPSR1 (0.35) | HPGDKDM4EUSP2KMT2AALDH1A1 | |
| SCHEMBL9039924 | 0.69 | KMT2A (0.34) | HPGDKDM4EUSP2TSHRL3MBTL1 | |
| SCHEMBL30987212 | 0.68 | CYP4F2 (0.41) | HPGDKDM4ETSHRTDP1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741733-A1 | PHENYLIMINO-THIADIAZABICYCLOALKANE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995021174-A1 | PHENYLIMINO-THIADIAZABICYCLOALKANE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1995-08-10 | — | — | WO | disclosed |