Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640033 | 0.91 | PLCG1 (0.42) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL7593231 | 0.91 | PLCG1 (0.42) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL9664427 | 0.91 | PLCG1 (0.42) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL9688291 | 0.91 | PLCG1 (0.42) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL9640039 | 0.91 | PLCG1 (0.42) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL9026674 | 0.90 | PLCG1 (0.40) | PLCG1RAB9AELANEHTTTDP1 | |
| SCHEMBL8645642 | 0.88 | PLCG1 (0.38) | PLCG1RAB9AELANETDP1L3MBTL1 | |
| SCHEMBL10382583 | 0.88 | PLCG1 (0.38) | PLCG1RAB9AELANETDP1L3MBTL1 | |
| SCHEMBL8645639 | 0.88 | PLCG1 (0.38) | PLCG1RAB9AELANETDP1L3MBTL1 | |
| SCHEMBL10013149 | 0.84 | PLCG1 (0.42) | PLCG1RAB9AELANEHTR2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5227376-A | Quaternary ammonium carbapenem antibiotics | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |