Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | CPT2 | P23786 | 1/20 | 0.46 |
| ▸ | CPT1A | P50416 | 1/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040494 | 0.88 | MRGPRX4 (0.48) | MRGPRX4PTPRCPTPN1PTPRFPTPN2 | |
| SCHEMBL9041398 | 0.86 | MRGPRX4 (0.49) | MRGPRX4PORCNCYP3A4KMT2ANAMPT | |
| SCHEMBL9041370 | 0.83 | CPT2 (0.63) | MRGPRX4PTPRCPTPN1PTPRFCPT2 | |
| SCHEMBL9042329 | 0.82 | CPT2 (0.61) | MRGPRX4PTPRCPTPN1PTPRFCPT2 | |
| SCHEMBL9042323 | 0.82 | CPT2 (0.61) | MRGPRX4PTPRCPTPN1PTPRFCPT2 | |
| SCHEMBL9043842 | 0.79 | PTPRC (0.58) | PTPRCPTPN1PTPRFCPT2CPT1A | |
| SCHEMBL9041623 | 0.79 | CPT2 (0.58) | MRGPRX4PTPRCPTPN1PTPRFCPT2 | |
| SCHEMBL9041609 | 0.79 | CPT2 (0.58) | MRGPRX4PTPRCPTPN1PTPRFCPT2 | |
| SCHEMBL9043116 | 0.79 | KDM4E (0.57) | PTPRCPTPN1PTPRFCPT2CPT1A | |
| SCHEMBL9043540 | 0.78 | PTPRC (0.69) | PTPRCPTPN1PTPRFCPT1BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |