Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042766 | 0.91 | PTPRC (0.47) | PTPRCPTPN1MAOBPTPN2PTPRF | |
| SCHEMBL9044244 | 0.82 | PTPRC (0.54) | PTPRCPTPN1MAOBPTPN2PTPRF | |
| SCHEMBL9042817 | 0.82 | L3MBTL1 (0.40) | PTPRCPTPN1MAOBALDH1A1PKM | |
| SCHEMBL9044383 | 0.79 | L3MBTL1 (0.39) | PTPRCPTPN1MAOBALDH1A1PKM | |
| SCHEMBL9044386 | 0.79 | L3MBTL1 (0.39) | PTPRCPTPN1MAOBALDH1A1PKM | |
| SCHEMBL9043749 | 0.79 | PTPRC (0.45) | PTPRCPTPN1MAOBPTPN2PTPRF | |
| SCHEMBL9042223 | 0.79 | FFAR1 (0.39) | PTPRCPTPN1MAOBALDH1A1L3MBTL1 | |
| SCHEMBL9042022 | 0.78 | PTPRC (0.37) | PTPRCPTPN1MAOBPTPN2KDM4E | |
| SCHEMBL9042326 | 0.78 | PTPN1 (0.41) | PTPRCPTPN1PTPN2PTPRFPKM | |
| SCHEMBL9043309 | 0.76 | HIF1A (0.40) | MAOBALDH1A1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | claimed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |