Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.49 |
| ▸ | CCNC | P24863 | 5/20 | 0.36 |
| ▸ | CDK8 | P49336 | 5/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 5/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042189 | 1.00 | ABCC9 (0.49) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL9042195 | 1.00 | ABCC9 (0.49) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL14307284 | 0.81 | ABCC9 (0.37) | ABCC9HASPIN | |
| SCHEMBL7886427 | 0.80 | ABCC9 (0.46) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL7886430 | 0.80 | ABCC9 (0.46) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL9363860 | 0.78 | ABCC9 (0.47) | ABCC9ABCB1 | |
| SCHEMBL9363847 | 0.78 | ABCC9 (0.47) | ABCC9ABCB1 | |
| SCHEMBL9363850 | 0.78 | ABCC9 (0.47) | ABCC9ABCB1 | |
| SCHEMBL7292872 | 0.77 | ABCC9 (0.46) | ABCC9CCNCCDK8HASPINCDK19 | |
| SCHEMBL7292871 | 0.77 | ABCC9 (0.46) | ABCC9CCNCCDK8HASPINCDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401010-B1 | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5140031-A | Pyranyl cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-08-18 | — | — | US | disclosed |