Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13413430 | 0.75 | CETP (0.56) | CETPNR1I2 | |
| SCHEMBL904254 | 0.74 | CETP (0.43) | CETPPTGDR2NR1I2 | |
| SCHEMBL15928258 | 0.73 | CETP (0.58) | CETPNR1I2 | |
| SCHEMBL5179065 | 0.73 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL532086 | 0.73 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL531717 | 0.73 | CETP (0.58) | CETPNR1I2 | |
| SCHEMBL904257 | 0.72 | CETP (0.45) | CETPPTGDR2 | |
| SCHEMBL3308361 | 0.70 | CETP (0.63) | CETPNR1I2 | |
| SCHEMBL531533 | 0.69 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL130307 | 0.68 | CETP (0.67) | CETPPTGDR2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |