Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904257 | 0.88 | CETP (0.45) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL531538 | 0.81 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL30002118 | 0.78 | HDAC3 (0.46) | CETP | |
| SCHEMBL40098 | 0.78 | HDAC3 (0.46) | CETP | |
| SCHEMBL904255 | 0.77 | CETP (0.52) | CETPPTGDR2TBXA2RPTGDRNR1I2 | |
| SCHEMBL904252 | 0.76 | CFTR (0.47) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL149712 | 0.75 | PTGDR2 (0.60) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL904262 | 0.74 | CETP (0.44) | CETPPTGDR2NR1I2 | |
| SCHEMBL531553 | 0.74 | CETP (0.63) | CETPNR1I2 | |
| SCHEMBL2500305 | 0.73 | PTGDR2 (0.57) | CETPPTGDR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |