Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041727 | 1.00 | KDM4E (0.46) | KDM4EKMT2ASMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9041974 | 0.84 | HPGD (0.46) | ADRB2ADRB1ADRB3HPGDLNPEP | |
| SCHEMBL9042657 | 0.84 | HPGD (0.46) | ADRB2ADRB1ADRB3HPGDLNPEP | |
| Hydrochloric Acid SCHEMBL9041285 | 0.83 | HPGD (0.46) | ADRB2ADRB1ADRB3HPGDLNPEP | |
| SCHEMBL10861854 | 0.80 | LTA4H (0.63) | SMN1; SMN2LTA4HLAP3RAB9A | |
| SCHEMBL9043043 | 0.80 | CACNA1B (0.51) | KDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9042525 | 0.80 | CACNA1B (0.51) | KDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL321228 | 0.78 | FOXM1 (0.63) | KDM4EKMT2ASMN1; SMN2LTA4HFOXM1 | |
| SCHEMBL10990120 | 0.75 | FOXM1 (0.53) | KDM4EKMT2ASMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9043198 | 0.74 | KDM4E (0.40) | KDM4EKMT2ASMN1; SMN2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |