SCHEMBL9043261

SCHEMBL9043261

CCCCCN(C(=O)NC1CCCCC1)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4OC(=O)OC(C)(C)C)cc3)c2c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.54
AGTR2 P50052 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9042894 0.99 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL9039681 0.99 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL9044192 0.98 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9040957 0.97 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9042590 0.95 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9041543 0.93 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9039860 0.92 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9042473 0.92 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL9041930 0.91 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL9043252 0.91 AGTR1 (0.58) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392317-B1 Benzimidazoles, drugs containing these compounds and process for their preparation THOMAE GMBH DR K (DE) 1996-01-03 EP disclosed
EP-0392317-A2 Benzimidazoles, drugs containing these compounds and process for their preparation Dr. Karl Thomae GmbH (DE) 1990-10-17 EP disclosed