Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044117 | 0.81 | HRH2 (0.34) | — | |
| SCHEMBL15017651 | 0.81 | HRH2 (0.34) | — | |
| SCHEMBL9044939 | 0.76 | CHEK1 (0.32) | CHEK1 | |
| SCHEMBL929673 | 0.72 | TACR3 (0.37) | — | |
| SCHEMBL19562888 | 0.67 | — | — | |
| SCHEMBL22776034 | 0.64 | KDM4E (0.46) | — | |
| SCHEMBL8819209 | 0.63 | RAB9A (0.46) | — | |
| SCHEMBL14160384 | 0.61 | KDM4E (0.45) | — | |
| SCHEMBL20851561 | 0.60 | CHRM4 (0.32) | — | |
| SCHEMBL20851575 | 0.60 | CHRM4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743944-A1 | AZACYCLIC DERIVATIVES | SmithKline Beecham Farmaceutici S.p.A. (IT) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021843-A1 | AZACYCLIC DERIVATIVES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1995-08-17 | — | — | WO | disclosed |