Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203122 | 1.00 | DPP4 (0.35) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL58103 | 1.00 | DPP4 (0.35) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL12203118 | 1.00 | DPP4 (0.35) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL57753 | 0.86 | DPP4 (0.41) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL16861355 | 0.86 | DPP4 (0.41) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL57769 | 0.86 | DPP4 (0.41) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL16861356 | 0.86 | DPP4 (0.41) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL88956 | 0.86 | DPP4 (0.41) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| Hydrochloric Acid SCHEMBL29511344 | 0.85 | DPP4 (0.40) | DPP4CYP2D6CYP2C19GLO1CYP2C9 | |
| SCHEMBL16169554 | 0.83 | TUBB1 (0.34) | CYP2D6CYP2C19GLO1CYP2C9TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309938-A1 | HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER | EISAI CO., LTD. (JP) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309938-A1 | HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER | DHCR7, HSD17B7, HCCS | DPP4 4723/4885CYP2D6 279/4885CYP2C19 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.