Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.80 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602848 | 1.00 | PRCP (0.80) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL3231149 | 0.95 | PRCP (0.88) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL6246208 | 0.95 | PRCP (0.88) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL7264385 | 0.95 | PRCP (0.88) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL5898615 | 0.94 | PRCP (0.91) | PRCPNAAATLR2GNAI3GNAO1 | |
| SCHEMBL5898616 | 0.92 | PRCP (0.89) | PRCPNAAATLR2GNAI3GNAO1 | |
| SCHEMBL23762418 | 0.90 | PRCP (0.97) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL9232625 | 0.90 | PRCP (0.97) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL3969872 | 0.90 | PRCP (0.69) | PRCPNAAADPP7TLR2GNAI3 | |
| SCHEMBL6360674 | 0.90 | PRCP (0.69) | PRCPNAAADPP7TLR2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749421-A1 | SULPHONAMIDE DERIVATIVES AS ASPARTYL PROTEASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 1996-12-27 | — | — | EP | disclosed |