SCHEMBL7264385

SCHEMBL7264385

CCCCNC(=O)C1CCCN1

nearest known ligand 0.88

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.88
DPP7 Q9UHL4 1/20 0.56
TLR2 O60603 2/20 0.55
GNAI3 P08754 1/20 0.49
GNAO1 P09471 1/20 0.49
GNAI1 P63096 1/20 0.49
NAAA Q02083 1/20 0.49
HTR2C P28335 2/20 0.45
HTR2B P41595 1/20 0.45
GAA P10253 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6246208 1.00 PRCP (0.88) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL9044288 0.95 PRCP (0.80) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL8602848 0.95 PRCP (0.80) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL23762418 0.95 PRCP (0.97) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL9232625 0.95 PRCP (0.97) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL11842693 0.94 PRCP (1.00) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL16618490 0.94 PRCP (1.00) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL5898619 0.94 PRCP (1.00) PRCPDPP7TLR2GNAI3GNAO1
SCHEMBL9825221 0.94 PRCP (1.00) PRCPDPP7TLR2GNAI3GNAO1
Bromide SCHEMBL11430734 0.94 PRCP (0.94) PRCPDPP7TLR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023513-A9 STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE UNIVERSITY OF MASSACHUSETTS (US) 2023-06-01 WO disclosed
WO-2023023513-A1 STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLEX USING ALKYLATED PHOSPHATE UNIVERSITY OF MASSACHUSETTS (US) 2023-02-23 WO disclosed
WO-2019013790-A1 ANTIMICROBIAL COMPOUNDS AND USES THEREOF CURZA GLOBAL, LLC (US) 2019-01-17 WO disclosed
WO-2019013789-A1 ANTIMICROBIAL COMPOUNDS CURZA GLOBAL, LLC (US) 2019-01-17 WO disclosed
US-20090321626-A1 LASER DESORPTION IONIZATION AND PEPTIDE SEQUENCING ON LASER INDUCED SILICON MICROCOLUMN ARRAYS THE GEORGE WASHINGTON UNIVERSITY 2009-12-31 US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed
US-4636567-A CNS DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-01-13 US disclosed
US-4610821-A CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-09-09 US disclosed
US-4610984-A CEREBRAL INSUFFICIENCY CASSELLA AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
US-4564609-A NERVOUS SYSTEM DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-01-14 US disclosed
EP-0123977-A1 Substituted piperazin-1-yl-acetic-acid amides, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-11-07 EP disclosed
EP-0123444-A1 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 PRCP 69/4885DPP7 267/4885TLR2 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.