Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962135 | 1.00 | MAPK10 (0.59) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL31390266 | 0.83 | MEN1 (0.59) | MAPK10MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL626575 | 0.83 | MEN1 (0.64) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL29582475 | 0.83 | MEN1 (0.64) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL2318964 | 0.82 | MEN1 (0.53) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL31138002 | 0.81 | MEN1 (0.61) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL3888498 | 0.80 | MEN1 (0.55) | MAPK10MEN1KMT2AGFERMAPT | |
| SCHEMBL904463 | 0.80 | MEN1 (0.55) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL21258999 | 0.80 | NPC1 (0.60) | MAPK10MEN1KMT2AGFERRAB9A | |
| SCHEMBL904444 | 0.80 | NPC1 (0.60) | MAPK10MEN1KMT2AGFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292230-B | Palladium catalyzed N-H carbonylation of N-phenylpyridine-2-amine with DMF as methyl source | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114292230-A | Palladium-catalyzed N-phenylpyridine-2-amine N-H carbonylation reaction taking DMF as methyl source | 桂林理工大学 | 2022-04-08 | — | — | CN | disclosed |
| US-20210087168-A1 | PROSTACYCLIN RECEPTOR AGONIST | MEDSHINE DISCOVERY INC. (CN) | 2021-03-25 | — | — | US | disclosed |
| EP-3750879-A1 | PROSTACYCLIN RECEPTOR AGONIST | Medshine Discovery Inc. (CN) | 2020-12-16 | — | — | EP | disclosed |
| CN-107973779-B | Preparation method of N- (2-pyridine/pyrimidine-based) indole derivative | 华侨大学 | 2020-05-05 | — | — | CN | disclosed |
| EP-2970260-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | Proximagen Limited (GB) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014140592-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |
| US-8778955-B2 | Indole derivatives or benzimidazole derivatives for modulating IkB kinase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-07-15 | — | — | US | disclosed |
| US-8778955-B2 | Indole derivatives or benzimidazole derivatives for modulating IkB kinase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-07-15 | — | — | US | disclosed |
| US-8778955-B2 | Indole derivatives or benzimidazole derivatives for modulating IkB kinase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-07-15 | — | — | US | disclosed |
| US-20050197353-A1 | Indole derivatives or benzimidazole derivatives for modulating IkB kinase | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-09-08 | — | — | US | disclosed |
| EP-1530568-A1 | INDOLE OR BENZIMIDAZOLE DERIVATIVES FOR MODULATING I&kB KINASE | Aventis Pharma Deutschland GmbH (DE) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022553-A1 | INDOLE OR BENZIMIDAZOLE DERIVATIVES FOR MODULATING IκB KINASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| US-6031106-A | Process and intermediate products for preparing pyridyl-4-fluoroanilines | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-6031106-A | Process and intermediate products for preparing pyridyl-4-fluoroanilines | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-6031106-A | Process and intermediate products for preparing pyridyl-4-fluoroanilines | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0888305-A1 | PROCESS AND INTERMEDIATE PRODUCTS FOR PREPARING PYRIDYL-4-FLUOROANILINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034872-A1 | PROCESS AND INTERMEDIATE PRODUCTS FOR PREPARING PYRIDYL-4-FLUOROANILINES | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087168-A1 | PROSTACYCLIN RECEPTOR AGONIST | PTGIR, TBXA2R, PTGFR | MAPK10 1439/4885MEN1 2717/4885KMT2A 3901/4885 |
| US-20050197353-A1 | Indole derivatives or benzimidazole derivatives for modulating IkB kinase | IKBKB, IKBKG, IKBKE | MAPK10 1055/4885MEN1 4096/4885KMT2A 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.