Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381737 | 0.98 | EPHX2 (0.40) | NPC1EPHX2LIPGNCF1CHRM1 | |
| SCHEMBL27013893 | 0.83 | NPC1 (0.43) | NPC1EPHX2HRH1CYP2D6HRH3 | |
| SCHEMBL27888454 | 0.83 | EPHX2 (0.46) | NPC1EPHX2LIPGALDH1A1 | |
| SCHEMBL9044462 | 0.82 | EPHX2 (0.37) | NPC1EPHX2LIPGCYP2D6CYP2C19 | |
| SCHEMBL27364774 | 0.82 | EPHX2 (0.37) | NPC1EPHX2LIPG | |
| SCHEMBL12049582 | 0.81 | NPC1 (0.42) | NPC1NCF1CHRM1CHRM2OPRM1 | |
| SCHEMBL1158572 | 0.81 | NCF1 (0.41) | NPC1NCF1CHRM1CHRM2OPRM1 | |
| SCHEMBL791729 | 0.79 | NPC1 (0.41) | NPC1NCF1CHRM1CHRM2OPRM1 | |
| SCHEMBL27536365 | 0.79 | EPHX2 (0.41) | NPC1EPHX2LIPGALDH1A1 | |
| SCHEMBL19959352 | 0.78 | SMN1; SMN2 (0.43) | NPC1LIPGCHRM1CHRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |