Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 6/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045010 | 0.85 | KDM5A (0.47) | KDM5AKDM4EHPGDKDM5BALDH1A1 | |
| SCHEMBL9044140 | 0.82 | KDM5A (0.47) | KDM5AKDM4EHPGDL3MBTL1KDM5B | |
| SCHEMBL9045877 | 0.80 | KDM5A (0.46) | KDM5ACFTRKDM4EHPGDL3MBTL1 | |
| SCHEMBL9044604 | 0.72 | KDM5A (0.50) | KDM5AKDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL9044437 | 0.71 | KDM5A (0.46) | KDM5AKDM4EHPGDKDM5BALDH1A1 | |
| SCHEMBL8677926 | 0.67 | GCGR (0.43) | KDM5AKDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL18347637 | 0.65 | CYP1A2 (0.55) | KDM4EHPGDL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL18152842 | 0.63 | CFTR (0.47) | CFTRKDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL8678382 | 0.62 | TLR7 (0.43) | KDM5AKDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11147953 | 0.61 | ADORA1 (0.46) | KDM5AKDM4EHPGDALDH1A1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579425-B1 | 6-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-09 | — | — | EP | claimed |
| US-5298481-A | 6-arylpyrimidines and herbicidal use | ROHM AND HAAS COMPANY (US) | 1994-03-29 | — | — | US | claimed |
| CN-1081439-A | 6-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-02-02 | — | — | CN | claimed |
| EP-0579425-A1 | 6-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | claimed |
| EP-0579425-B1 | 6-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-09 | — | — | EP | disclosed |