Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044587 | 0.85 | KDM5A (0.46) | KDM5AKDM4EALDH1A1HPGDADORA2B | |
| SCHEMBL9044604 | 0.82 | KDM5A (0.50) | KDM5AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9044437 | 0.78 | KDM5A (0.46) | KDM5AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11808587 | 0.71 | ADORA1 (0.51) | KDM4EALDH1A1GAAHPGDADORA2B | |
| SCHEMBL9044140 | 0.71 | KDM5A (0.47) | KDM5AKDM4EALDH1A1HPGDADORA2B | |
| SCHEMBL23105448 | 0.70 | CNR1 (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9045877 | 0.69 | KDM5A (0.46) | KDM5AKDM4EALDH1A1HPGDADORA2B | |
| SCHEMBL14953694 | 0.69 | CNR1 (0.41) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL9045892 | 0.67 | CYP1A2 (0.58) | KDM5AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL6979700 | 0.66 | KDM4E (0.60) | KDM4EALDH1A1CYP1A2USP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579425-B1 | 6-arylpyrimidines and herbicidal use thereof | ROHM & HAAS (US) | 1996-10-09 | — | — | EP | claimed |