Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 0.83 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.83 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.83 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.83 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.83 |
| ▸ | BCHE | P06276 | 1/20 | 0.83 |
| ▸ | ACHE | P22303 | 1/20 | 0.83 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.82 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.82 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.82 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leachianone A SCHEMBL29415618 | 1.00 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| Leachianone A SCHEMBL27013422 | 1.00 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| Leachianone A SCHEMBL30766171 | 1.00 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| SCHEMBL15386077 | 0.96 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| SCHEMBL27013509 | 0.96 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| SCHEMBL31237251 | 0.96 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| SCHEMBL15452193 | 0.96 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| SCHEMBL10307770 | 0.93 | BACE1 (0.86) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| Kurarinone SCHEMBL904627 | 0.91 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 | |
| Kurarinone SCHEMBL10307523 | 0.91 | BACE1 (1.00) | BACE1ESR1SLC5A1SLC5A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9326968-B2 | Composition for enhancing immunity containing compounds represented by chemical formulas 1-8 or sophora flavescens extract as active ingredient | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-05-03 | — | — | US | disclosed |
| US-9326968-B2 | Composition for enhancing immunity containing compounds represented by chemical formulas 1-8 or sophora flavescens extract as active ingredient | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-05-03 | — | — | US | disclosed |
| US-9326968-B2 | Composition for enhancing immunity containing compounds represented by chemical formulas 1-8 or sophora flavescens extract as active ingredient | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-05-03 | — | — | US | disclosed |
| US-20130303474-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING COMPOUNDS REPRESENTED BY CHEMICAL FORMULAS 1-8 OR SOPHORA FLAVESCENS EXTRACT AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECH (KR) | 2013-11-14 | — | — | US | disclosed |
| US-20130303474-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING COMPOUNDS REPRESENTED BY CHEMICAL FORMULAS 1-8 OR SOPHORA FLAVESCENS EXTRACT AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECH (KR) | 2013-11-14 | — | — | US | disclosed |
| US-20130303474-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING COMPOUNDS REPRESENTED BY CHEMICAL FORMULAS 1-8 OR SOPHORA FLAVESCENS EXTRACT AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECH (KR) | 2013-11-14 | — | — | US | disclosed |
| WO-2012043949-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING COMPOUNDS REPRESENTED BY CHEMICAL FORMULAS 1-8 OR SOPHORA FLAVESCENS EXTRACT AS ACTIVE INGREDIENT | 한국생명공학연구원 (KR) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303474-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING COMPOUNDS REPRESENTED BY CHEMICAL FORMULAS 1-8 OR SOPHORA FLAVESCENS EXTRACT AS ACTIVE INGREDIENT | IRF3, IFNG, IRF2BP2 | BACE1 242/4885ESR1 2901/4885SLC5A1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.