Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044687 | 1.00 | TBXA2R (0.67) | TBXA2RTBXAS1 | |
| SCHEMBL9047398 | 1.00 | TBXA2R (0.67) | TBXA2RTBXAS1 | |
| SCHEMBL9046608 | 0.92 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL9046600 | 0.92 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL9045812 | 0.90 | TBXA2R (0.58) | TBXA2RTBXAS1 | |
| SCHEMBL9045798 | 0.90 | TBXA2R (0.58) | TBXA2RTBXAS1 | |
| SCHEMBL9047907 | 0.87 | TBXA2R (0.66) | TBXA2RTBXAS1 | |
| SCHEMBL9316653 | 0.87 | TBXA2R (0.66) | TBXA2RTBXAS1 | |
| SCHEMBL9046034 | 0.86 | TBXA2R (0.52) | TBXA2RTBXAS1 | |
| SCHEMBL9046039 | 0.86 | TBXA2R (0.52) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345747-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5302602-A | 5-HETEROCYCLO-ALKYL SUBSTITUTED DIBENZO (A,D) CYCLOHEPTENES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5302596-A | DIBENZO-CYCLOHEPTENES,-OXEPINS AND-THIEPINS SUBSTITUTED BY A HETEROCYCLO-ALKYL | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0325755-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5242931-A | Antiischemic agents and cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5143922-A | Tricyclic thromboxane A2 antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-5118701-A | Antiischemic agents, anticoagulants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4999363-A | Inhibit biosynthesis of thromboxane A2 | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4994463-A | Antiallegens, antihistamines, antiischemic agents and cardiovasculat disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0345747-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0325755-A1 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |