Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.66 |
| ▸ | PTPRC | P08575 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042056 | 0.95 | FFAR1 (0.65) | PLA2G4BFFAR1PTPRCPTPN1NR1H4 | |
| SCHEMBL9040124 | 0.90 | FFAR1 (0.64) | PLA2G4BFFAR1PTPRCPTPN1PTPN2 | |
| SCHEMBL9042067 | 0.89 | PTPRC (0.67) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL2312866 | 0.87 | PLA2G4B (0.83) | PLA2G4BFFAR1NR1H4S1PR1S1PR3 | |
| SCHEMBL9042859 | 0.87 | PTPRC (0.65) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL9043699 | 0.87 | PTPRC (0.65) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL9041063 | 0.87 | PTPRC (0.65) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL9042501 | 0.87 | PTPRC (0.65) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL9402815 | 0.87 | PTPRC (0.65) | PLA2G4BPTPRCPTPN1PTPN2PTPRF | |
| SCHEMBL9042801 | 0.87 | PTPRC (0.53) | PLA2G4BFFAR1PTPRCPTPN1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |