Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.83 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366698 | 0.98 | PLA2G4B (0.86) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| SCHEMBL4373447 | 0.98 | PLA2G4B (0.86) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| Hydrochloric Acid SCHEMBL4253646 | 0.98 | PLA2G4B (0.81) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| SCHEMBL4361279 | 0.95 | PLA2G4B (0.76) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| SCHEMBL4327125 | 0.90 | PKM (0.73) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| SCHEMBL14383956 | 0.88 | S1PR1 (0.70) | PLA2G4BFFAR1PKMNR1H4NR4A1 | |
| SCHEMBL14966915 | 0.88 | PKM (0.71) | PLA2G4BFFAR1PKMNR1H4PLA2G2A | |
| SCHEMBL7774930 | 0.88 | NR4A2 (0.77) | PLA2G4BFFAR1PKMNR4A1NR4A2 | |
| SCHEMBL11727340 | 0.87 | L3MBTL1 (0.72) | PLA2G4BFFAR1NR1H4S1PR1S1PR3 | |
| SCHEMBL9044748 | 0.87 | PLA2G4B (0.66) | PLA2G4BFFAR1PKMNR1H4PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623901-A | Preparation method of p-phenylbutoxy benzoic acid | 泰兴中科艾德膜材料科技有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-111302930-B | Preparation method of p-phenylbutoxy benzoic acid | 湖南复瑞生物医药技术有限责任公司 | 2023-11-07 | — | — | CN | claimed |
| CN-219209942-U | Reaction device for preparing p-phenylbutoxy benzoic acid | 泰兴中科艾德膜材料科技有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-111592451-B | Preparation method of 4- (4-phenylbutoxy) benzoic acid | 昆山力田医化科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-108558916-B | Synthesis process of p-phenylbutoxy benzoic acid | 昆山力田医化科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-111592451-A | Preparation method of 4- (4-phenylbutoxy) benzoic acid | 昆山力田医化科技有限公司 | 2020-08-28 | — | — | CN | claimed |
| CN-111410600-A | Preparation method of p-phenylbutoxy benzoic acid | 安徽省诚联医药科技有限公司 | 2020-07-14 | — | — | CN | claimed |
| CN-111302930-A | Preparation method of p-phenylbutoxy benzoic acid | 湖南复瑞生物医药技术有限责任公司 | 2020-06-19 | — | — | CN | claimed |
| CN-106588897-A | New preparation method of Pranlukast | 上海微巨实业有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-104402710-B | Pranlukast intermediate 4-(4-phenylbutoxy) benzoic synthesis new way | 济南大学 | 2016-06-22 | — | — | CN | claimed |
| CN-103588638-B | A kind of 4-(benzene butoxy) benzoic synthetic method | Taizhou plain Huading chemical industry company limited (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-104402710-A | Novel synthesis route of pranlukast intermediate 4-(4-phenylbutoxyl)benzoic acid | UNIV JINAN | 2015-03-11 | — | — | CN | claimed |
| CN-103588638-A | Method for synthetizing 4-(benzene butoxy) benzoic acid | Taizhou huading chemical industry co ltd | 2014-02-19 | — | — | CN | claimed |
| CN-101450943-B | Method for synthesizing drug pranlukast from tetrahydrofuran path | UNIV HEBEI SCIENCE & TECH | 2012-11-07 | — | — | CN | claimed |
| CN-101560208-A | Preparation method of pranlukast | ANHUI AXING FOODS CO LTD (CN) | 2009-10-21 | — | — | CN | claimed |
| CN-101450943-A | Method for synthesizing drug pranlukast from tetrahydrofuran path | UNIV HEBEI SCIENCE & TECH (CN) | 2009-06-10 | — | — | CN | claimed |
| JP-7025819-A | — | — | None | — | — | JP | disclosed |
| JP-3258759-A | — | — | None | — | — | JP | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |