SCHEMBL904480

SCHEMBL904480

O=[C]C(Cc1ccc(O)cc1)NI

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
SLC6A2 P23975 1/20 0.41
ESR1 P03372 10/20 0.41
ESR2 Q92731 10/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL904481 1.00 SLC7A5 (0.42) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL900060 0.83 SLC7A5 (0.43) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL900062 0.83 SLC7A5 (0.43) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL2639452 0.81 TAAR1 (0.46) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL2639451 0.81 TAAR1 (0.46) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL9539354 0.81 SLC7A5 (0.46) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL9539351 0.81 SLC7A5 (0.46) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL7517353 0.81 TAAR1 (0.46) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL8776731 0.81 CTSC (0.42) SLC7A5TAAR1SLC6A2MEN1CYP1A2
SCHEMBL8776735 0.81 CTSC (0.42) SLC7A5TAAR1SLC6A2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1642588-A2 Mimetics of interleukin-8 and methods of using them in the prevention, treatment, diagnosis, and ameliorization of symptoms of a disease Chemokine Therapeutics Corporation (CA) 2006-04-05 EP claimed
CN-118202041-A Background specific adenine base editor and application thereof 布罗德研究所股份有限公司 2024-06-14 CN disclosed
CN-116685682-A Guided editing guide RNAs, compositions thereof, and methods of using the same 布罗德研究所股份有限公司 2023-09-01 CN disclosed
CN-116490610-A Methods and compositions for modulating genome 旗舰先锋创新VI有限责任公司 2023-07-25 CN disclosed
CN-116209770-A Methods and compositions for modulating genomic improvement 旗舰先锋创新VI有限责任公司 2023-06-02 CN disclosed
CN-116209756-A Methods and compositions for modulating genome 旗舰先锋创新VI有限责任公司 2023-06-02 CN disclosed
CN-116096873-A Methods and compositions for editing two strands of a target double-stranded nucleotide sequence simultaneously 布罗德研究所股份有限公司 2023-05-09 CN disclosed
WO-2023280331-A1 INSULIN DERIVATIVES WITH ENHANCED THERMAL STABILITY USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2023-01-12 WO disclosed
CN-108303546-B Method for identifying thyroid disease risk 基酶有限公司 2023-01-03 CN disclosed
CN-114127285-A Methods and compositions for editing nucleotide sequences 布罗德研究所股份有限公司 2022-03-01 CN disclosed
WO-1996028471-A1 MODULATORS OF AMYLOID AGGREGATION PRAECIS PHARMACEUTICALS INCORPORATED (US) 1996-09-19 WO disclosed
WO-1995020317-A1 METHOD FOR MAKING UNIVERSAL DONOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-08-03 WO disclosed
EP-0452040-B1 Polysaccharide compounds produced by fermentation KYOWA HAKKO KOGYO KK (JP) 1995-07-12 EP disclosed
US-5252342-A Administering prior to or concurrrently THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-10-12 US disclosed
EP-0460100-A1 LIPOSOME GEL COMPOSITION AND METHOD LIPOSOME TECHNOLOGY, INC. (US) 1991-12-11 EP disclosed
EP-0452040-A2 Polysaccharide compounds produced by fermentation KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1991-10-16 EP disclosed
EP-0405763-A1 GRF peptides MALLINCKRODT VETERINARY LIMITED (GB) 1991-01-02 EP disclosed
WO-1990015073-A1 GRF PEPTIDES COOPERS ANIMAL HEALTH LIMITED (GB) 1990-12-13 WO disclosed
WO-1990009782-A1 LIPOSOME GEL COMPOSITION AND METHOD LIPOSOME TECHNOLOGY, INC. (US) 1990-09-07 WO disclosed
US-4944948-A EPIDERMAL GROWTH FACTOR AS A WOUND HEALING AGENT; SUSTAINED RELEASE LIPOSOME TECHNOLOGY, INC. (US) 1990-07-31 US disclosed