Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401698 | 0.90 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2401695 | 0.90 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27543972 | 0.86 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1737308 | 0.85 | TYMP (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5505017 | 0.84 | TYMP (0.51) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5505015 | 0.84 | TYMP (0.51) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL7527348 | 0.83 | P2RY6 (0.53) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5710025 | 0.82 | TYMP (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL17223094 | 0.82 | TYMP (0.51) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL31390283 | 0.81 | TYMP (0.49) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |