Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935824 | 0.82 | CTBP2 (0.58) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL80264 | 0.81 | CTBP2 (0.53) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL29631318 | 0.80 | AKR1B1 (0.61) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL8285 | 0.80 | AKR1B1 (0.61) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL30446395 | 0.80 | CTBP2 (0.56) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL14651444 | 0.80 | GABRA1 (0.44) | SHBGPTGS2POLB | |
| SCHEMBL2528595 | 0.80 | AKR1B1 (0.61) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL9772469 | 0.80 | CTBP2 (0.56) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL1259145 | 0.80 | CTBP2 (0.56) | CTBP2KMT2AMEN1MAPTSHBG | |
| SCHEMBL782187 | 0.80 | CTBP2 (0.56) | CTBP2KMT2AMEN1MAPTSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641207-A4 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF. | SCRIPPS RESEARCH INST (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5527805-A | DNA-CLEAVING, CYTOTOXIC AND ANTI-TUMOR COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0641207-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5281710-A | Antibiotics or antitumor agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993023046-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |