Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512944 | 0.86 | CYP4F2 (0.32) | TSHRTDP1ALDH1A1HSD17B10CYP4F2 | |
| SCHEMBL14196625 | 0.81 | TSHR (0.36) | TSHRTDP1ALDH1A1HSD17B10CYP4F2 | |
| SCHEMBL27570680 | 0.76 | ALDH1A1 (0.33) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL3059758 | 0.74 | HSD17B10 (0.33) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL15165 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL6690279 | 0.73 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL29291915 | 0.73 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL4679417 | 0.72 | TSHR (0.40) | TSHRTDP1ALDH1A1HSD17B10 | |
| Methyl Alcohol SCHEMBL28449343 | 0.72 | TSHR (0.40) | TSHRTDP1ALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28163619 | 0.71 | CYP4F2 (0.38) | ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522376-B1 | Process for the manufacture of polyalkylmethacrylate-macromonomers | ROEHM GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5254632-A | Method of manufacturing polyalkyl methacrylate macromonomers, and use of same in the manufacture of comb polymers | ROHM GMBH CHEMISCHE FABRIK (DE) | 1993-10-19 | — | — | US | disclosed |
| EP-0522376-A1 | Process for the manufacture of polyalkylmethacrylate-macromonomers | RÖHM GMBH (DE) | 1993-01-13 | — | — | EP | disclosed |