Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 14/20 | 0.62 |
| ▸ | HTR1B | P28222 | 12/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875034 | 0.85 | HTR1D (0.84) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL7441439 | 0.82 | HTR1D (0.69) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL7439194 | 0.80 | HTR1D (0.84) | HTR1DHTR1BHTR1A | |
| SCHEMBL7448912 | 0.80 | HTR1D (0.84) | HTR1DHTR1BHTR1A | |
| SCHEMBL7442979 | 0.80 | HTR1D (0.85) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL8124390 | 0.78 | HTR1D (0.83) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL8317482 | 0.75 | HTR1D (0.74) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL7434651 | 0.73 | HTR1D (0.83) | HTR1DHTR1BDRD2 | |
| SCHEMBL7441015 | 0.72 | HTR1D (0.69) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL8314559 | 0.71 | HTR1D (1.00) | HTR1DHTR1BDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690843-A1 | INDOLETETRALINS HAVING DOPAMINERGIC ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 1996-01-10 | — | — | EP | disclosed |