Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680481 | 0.91 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL9044700 | 0.89 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL7678011 | 0.87 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7680512 | 0.86 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL7680751 | 0.86 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL9047399 | 0.86 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7684872 | 0.84 | CRHR1 (0.68) | CRHR1 | |
| SCHEMBL7680501 | 0.84 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7687264 | 0.82 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL7680614 | 0.82 | CRHR1 (0.73) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |