Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 6/20 | 0.41 |
| ▸ | KDM4B | O94953 | 6/20 | 0.41 |
| ▸ | KDM5C | P41229 | 6/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL30909062 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9049148 | 0.88 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9048518 | 0.87 | OPRM1 (0.58) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9046671 | 0.86 | OPRM1 (0.51) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9044366 | 0.84 | OPRM1 (0.51) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Phthalic Acid SCHEMBL30909196 | 0.83 | OPRM1 (0.53) | OPRM1OPRK1HTR6HTR7DRD2 | |
| Phthalic Acid SCHEMBL9045536 | 0.83 | OPRM1 (0.53) | OPRM1OPRK1HTR6HTR7DRD2 | |
| Oxalic Acid SCHEMBL9034341 | 0.82 | OPRM1 (0.54) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9048237 | 0.82 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| SCHEMBL7452535 | 0.81 | OPRM1 (0.57) | OPRM1OPRK1OPRL1HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |