Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 15/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048564 | 0.86 | CHRM2 (0.48) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL9045695 | 0.86 | MTNR1A (0.44) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL9047872 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL9050297 | 0.84 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL9049012 | 0.82 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL8858465 | 0.81 | PTGIR (0.64) | PTGIR | |
| SCHEMBL9048206 | 0.81 | PTGIR (0.48) | CHRM2CHRM1CHRM3PTGIRCA1 | |
| SCHEMBL8858425 | 0.80 | MTNR1A (0.43) | CHRM2CHRM1CHRM3PTGIRMTNR1A | |
| SCHEMBL9048748 | 0.77 | PTGIR (0.49) | CHRM2CHRM1CHRM3PTGIRCA1 | |
| SCHEMBL9049235 | 0.77 | PTGIR (0.44) | CHRM2CHRM1CHRM3PTGIRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |