Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583340 | 0.86 | AGTR1 (0.41) | PPARGAGTR1AGTR2 | |
| SCHEMBL9046866 | 0.84 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9045732 | 0.82 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9141104 | 0.81 | AGTR1 (0.44) | PPARGAGTR1AGTR2 | |
| SCHEMBL9045634 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9047004 | 0.81 | AGTR1 (0.41) | PPARGAGTR1AGTR2 | |
| SCHEMBL9043684 | 0.80 | AGTR1 (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9043884 | 0.79 | AGTR1 (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL9558461 | 0.79 | AGTR1 (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL9146900 | 0.78 | AGTR1 (0.45) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531876-B1 | Imidazoindolizine derivatives and process for preparation thereof | TANABE SEIYAKU CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5268377-A | Imidazoindolizine derivatives process for preparation thereof and use thereof to treat hypertension | TANABE SEIYAKU CO., LTD. (JP) | 1993-12-07 | — | — | US | disclosed |
| EP-0531876-A2 | Imidazoindolizine derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |