Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324373 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7752451 | 0.86 | ALDH1A1 (0.34) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7658017 | 0.86 | ALDH1A1 (0.34) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7752222 | 0.83 | ALDH1A1 (0.37) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7669944 | 0.83 | ALDH1A1 (0.37) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7662120 | 0.81 | ALDH1A1 (0.36) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8405604 | 0.80 | CHRNA1 (0.38) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8556153 | 0.78 | ATM (0.39) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL14354912 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27300632 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0366085-A2 | Tetrahydropyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-02 | — | — | EP | disclosed |