Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylene Glycol Monoethyl Ether SCHEMBL10946555 | 0.97 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL9789370 | 0.97 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Triethylene Glycol SCHEMBL21811317 | 0.97 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| 2-Methoxyethanol SCHEMBL29208297 | 0.97 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11436530 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL8576276 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL3457519 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL20836247 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL10820929 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL9045839 | 0.92 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514917-B1 | Process for and 2-(cyanoimino)-quinazoline derivatives useful as intermediates in the preparation of 6,7-di-(chloro)-1,5-di(hydro)-imidazo-[2,1-b]quinazolin-2[3H]-one and process for preparing the 2-(cyanoimino)-quinazoline derivatives | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-12-27 | — | — | EP | disclosed |
| US-5391737-A | Process for the preparation of 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2[3H]-one | EGIS GYOGYSZERGYAR (HU) | 1995-02-21 | — | — | US | disclosed |
| EP-0514917-A1 | Process for and 2-(cyanoimino)-quinazoline derivatives useful as intermediates in the preparation of 6,7-di-(chloro)-1,5-di(hydro)-imidazo-[2,1-b]quinazolin-2[3H]-one and process for preparing the 2-(cyanoimino)-quinazoline derivatives | EGIS GYOGYSZERGYAR (HU) | 1992-11-25 | — | — | EP | disclosed |