SCHEMBL9045894

SCHEMBL9045894

Cc1cc2c(N)c(F)cc(F)c2o1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21003357 0.71 ALDH1A1 (0.37) ALDH1A1
SCHEMBL26756454 0.69 ALDH1A1 (0.37) ALDH1A1
SCHEMBL25162229 0.65 ALDH1A1 (0.36) ALDH1A1
SCHEMBL19885236 0.64 POLB (0.39) ALDH1A1
SCHEMBL5814455 0.64 CA1 (0.38) ALDH1A1
SCHEMBL12728542 0.64 MAPT (0.40) ALDH1A1
SCHEMBL15142199 0.63 ALDH1A1 (0.44) ALDH1A1
SCHEMBL2152858 0.63 ESR1 (0.32) ALDH1A1
SCHEMBL16005132 0.63 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3605156 0.63 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476697-B1 Benzofuranyl- and benzothiophenyl substituted uracil derivatives, and their production and use as herbicides SUMITOMO CHEMICAL CO (JP) 1996-03-20 EP disclosed
US-5169431-A Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-12-08 US disclosed
EP-0476697-A1 Benzofuranyl- and benzothiophenyl substituted uracil derivatives, and their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-03-25 EP disclosed