SCHEMBL904651

SCHEMBL904651

NCc1cccnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5008501 0.98 DPP4 (0.53)
Hydrochloric Acid SCHEMBL3294123 0.98 DPP4 (0.53)
SCHEMBL30663575 0.83
SCHEMBL31051602 0.79
SCHEMBL669824 0.79
SCHEMBL23852687 0.77
SCHEMBL580627 0.77
SCHEMBL14420866 0.77
Hydrochloric Acid SCHEMBL5036129 0.77 CASP3 (0.42)
SCHEMBL7216879 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9176121-A None JP disclosed
CN-116254304-B Application of nitrilase in selective catalysis of 6-chloronicotinyl nitrile to synthesize 6-chloronicotinic acid and mutant 浙江工业大学 2026-04-28 CN disclosed
CN-114196658-B Nitrilase mutant and application thereof in catalytic synthesis of 2-chloronicotinic acid 浙江工业大学 2023-09-05 CN disclosed
CN-114196658-B Nitrilase mutant and application thereof in catalytic synthesis of 2-chloronicotinic acid 浙江工业大学 2023-09-05 CN disclosed
US-11737463-B2 Pyridine and pyrazine compounds BASF SE (DE) 2023-08-29 US disclosed
CN-116254304-A Application of nitrilase in selective catalysis of 6-chloronicotinyl nitrile to synthesize 6-chloronicotinic acid and mutant 浙江工业大学 2023-06-13 CN disclosed
CN-115746034-A Three-function organic catalyst, preparation method and application thereof 浙江大学 2023-03-07 CN disclosed
US-20220048889-A1 HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-17 US disclosed
CN-113087660-A Organic bifunctional catalyst and preparation method thereof, and stereoregular biodegradable polyester and preparation method thereof 中国科学院长春应用化学研究所 2021-07-09 CN disclosed
US-20210145002-A1 PYRIDINE AND PYRAZINE COMPOUNDS BASF SE (DE) 2021-05-20 US disclosed
US-20050010048-A1 Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors ZHUANG LINGHANG (US) 2005-01-13 US disclosed
US-20040158067-A1 3-substituted-6-aryl pyridines NEUROGEN CORPORATION 2004-08-12 US disclosed
WO-2004043925-A2 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS NEUROGEN CORPORATION (US) 2004-05-27 WO disclosed
EP-1391450-A1 N-(HETEROCYCLE-METHYL)ALKYLAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND BACTERICIDE Kureha Chemical Industry Co., Ltd. (JP) 2004-02-25 EP disclosed
EP-1333831-A2 AZA-AND POLYAZA-NAPHTHALENYL KETONES USEFUL AS HIV INTEGRASE INHIBITORS Merck & Co., Inc. (US) 2003-08-13 EP disclosed
WO-2002036734-A2 AZA-AND POLYAZA-NAPHTHALENYL KETONES USEFUL AS HIV INTEGRASE INHIBITORS MERCK & CO., INC. (US) 2002-05-10 WO disclosed
US-6271385-B1 FUNGICIDES (SUCH AS THOSE FOR USE IN FARMING AND HORTICULTURE). KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-07 US disclosed
EP-1020441-A1 N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed
JP-H09176121-A PRODUCTION OF CHLORO-(AMINOMETHYL)PYRIDINES KOEI CHEM CO LTD 1997-07-08 JP disclosed
US-5026864-A Preparation of 2-chloro-5-aminomethyl-pyridine BAYER AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed