⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117982 | 0.83 | — | — | |
| SCHEMBL6140059 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL9860693 | 0.78 | — | — | |
| SCHEMBL446887 | 0.73 | — | — | |
| SCHEMBL2011304 | 0.73 | — | — | |
| SCHEMBL5446574 | 0.73 | — | — | |
| SCHEMBL5915891 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL787874 | 0.65 | — | — | |
| SCHEMBL15359393 | 0.62 | — | — | |
| SCHEMBL23302398 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061761-B1 | A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE | Baker Instruments Corporation (US) | 1988-05-18 | — | — | EP | claimed |
| US-4520101-A | FERMENTATION WITH ADDITION OF PHOSPHORUS COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | claimed |
| JP-8127792-A | — | — | None | — | — | JP | disclosed |
| US-10730904-B2 | Method for liquid-phase synthesis of nucleic acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| EP-2921499-B1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS | TAKEDA PHARMACEUTICALS CO (JP) | 2020-01-22 | — | — | EP | disclosed |
| US-20190135852-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-09 | — | — | US | disclosed |
| CN-104918949-B | The liquid-phase synthesis process of nucleic acid | 武田药品工业株式会社 | 2017-10-10 | — | — | CN | disclosed |
| US-20150315229-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-05 | — | — | US | disclosed |
| EP-2921499-A1 | METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID | Takeda Pharmaceutical Company Limited (JP) | 2015-09-23 | — | — | EP | disclosed |
| CN-104918949-A | Method for liquid-phase synthesis of nucleic acid | TAKEDA PHARMACEUTICAL | 2015-09-16 | — | — | CN | disclosed |
| JP-H08127792-A | LUBRICATING OIL COMPOSITION FOR REFRIGERATOR | MATSUSHITA ELECTRIC IND CO LTD | 1996-05-21 | — | — | JP | disclosed |
| EP-0061761-B1 | A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE | Baker Instruments Corporation (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4520101-A | FERMENTATION WITH ADDITION OF PHOSPHORUS COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| US-4495346-A | CATALYTICALLY COUPLING TWO MONOSACCHARIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-01-22 | — | — | US | disclosed |
| US-4347360-A | Ring open nucleoside analogues | ENS BIO LOGICALS INC. (CA) | 1982-08-31 | — | — | US | disclosed |