Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045271 | 0.87 | GABRA1 (0.37) | CLCN2KDM4EALDH1A1HTTBID | |
| SCHEMBL11121932 | 0.87 | CLCN2 (0.47) | CLCN2HMGB1FOLH1KDM4EALDH1A1 | |
| SCHEMBL433916 | 0.84 | KAT8 (0.55) | KDM4EHSD17B10BIDMCL1BCL2L1 | |
| SCHEMBL11244096 | 0.84 | CLCN2 (0.45) | CLCN2HMGB1FOLH1KDM4EALDH1A1 | |
| SCHEMBL9045316 | 0.83 | HPGD (0.50) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL15344588 | 0.83 | CLCN2 (0.50) | CLCN2HMGB1FOLH1HTTBID | |
| Ammonia Solution, Strong SCHEMBL7713478 | 0.83 | KAT8 (0.54) | KDM4EHSD17B10BIDMCL1BCL2L1 | |
| SCHEMBL9645012 | 0.83 | HTT (0.50) | CLCN2FOLH1ALDH1A1HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL7713477 | 0.83 | KAT8 (0.54) | KDM4EHSD17B10BIDMCL1BCL2L1 | |
| SCHEMBL11221238 | 0.83 | CLCN2 (0.44) | CLCN2HMGB1FOLH1SLC16A3BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |